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PROTO-ONCOGENE PROTEINS P21(RAS)
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DeCS
Descriptor
English
:
Proto-Oncogene Proteins p21(ras)
Descriptor
Spanish
:
Proteínas Proto-Oncogénicas p21(ras)
Descriptor
Portuguese
:
Proteínas Proto-Oncogênicas p21(ras)
Synonyms
English
:
Proto-Oncogene Proteins c-ras
c-Ha-ras p21
c-Ki-ras p21
p21(c-Ha-ras)
p21(c-Ki-ras)
p21(c-ras)
p21(N-ras)
p21(ras)
ras Proto-Oncogene Protein p21
Tree Number:
D08.811.277.040.330.300.400.500.600
D12.644.360.525.500.600
D12.776.157.325.515.500.600
D12.776.476.525.500.600
D12.776.624.664.700.200
Definition
English
:
Cellular
proteins
encoded by the H-ras, K-ras and N-ras
genes
. The
proteins
have GTPase activity and is involved in
signal transduction
as a
monomeric GTP-binding proteins
. Elevated levels of p21 c-ras have been associated with neoplasia. This enzyme was formerly listed as EC 3.6.1.47.
History Note
English
:
2006(1991)
Allowable Qualifiers
English
:
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
ultrastructure
urine
Record Number:
29090
Unique Identifier:
D016283
Occurrence in VHL
:
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